New St. Jude research could lead to promising sickle cell treatment - New Mexico Business Weekly:

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The researchers used a strain of mouse cellw with basically the same genetic defect and symptomes as humans with sickle cell They thenintroduced altered, corrective cells into the mice. Results of the St. Jude experiments have been reporte d in the online issuw of thejournal . "Whenj we examined the treatexd mice, we could detect little, if any, diseaser using our methods," said St. Jude’s Derek Persons, the paper'zs senior author. "The mice showedc no anemia, and thei organ function was essentially The scientists caution that applying the gene therapg to humans presents significanttechnical obstacles.
However, they believre that the new therapy will become an importantr treatment for the Sickle cell disease affects millions ofpeople It’s caused by a tiny genetic defect in the body’ss blood-making process. This defect causes some red bloodf cellsto deform, clump, break apart and clog bloof vessels. This can caus strokes and damage liver, spleen and lungs. So far, the only treatmeng of the disease is a bone marrow Basedin Memphis, is a leading pediatricv treatment and research facility focused on children's catastrophic It employs more than 3,0009 in Memphis.